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Variable number of tandemrepeats (VNTR polymorphisms) of insulin gene (INS) represent around 10% of geneticpredisposition to T1D and a lot of other genes, especially associated with the regulation ofimmune system, have been identified (CTLA-4, FOXP3, CCR5, IL2RA, PTPN22, ITPR3,OAS1, SUMO4).

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